Higher Adenoma Detection Rates with Endocuff-Assisted Colonoscopy A Randomized Controlled Multicenter Trial
Martin Floer, Erwin Biecker, Rudiger Fitzlaff, Hermann Röming, Detlev Ameis, Achim Heinecke, Steffen Kunsch, Volker Ellenrieder, Philipp Ströbel, Michael Schepke, Tobias Meister PLoS ONE 9(12): e114267. doi:10.1371/journal.pone. 0114267
This four centre prospective trial randomised 500 subjects to standard colonoscopy or ENDOCUFF™ assisted colonoscopy the primary outcome measure was the adenoma detection rate (ADR). The ADR increased from 21% to 35% with the use of the ENDOCUFF™ (p = 0.0001) an absolute increase of 14% and a relative improvement of 74%. The total number of adenomas detected rose from 88 to 144, a relative improvement of 64%.The procedure and withdrawal times did not differ. Caecal and ileum intubation rates were similar. No major adverse events occurred in either group.
Conclusion: the ENDOCUFF™ is safe, and substantially improves adenoma detection and removal without lengthening operator time or reducing caecal or ileal intubation.