Novel Endocuff-assisted Colonoscopy Significantly Increases the Polyp Detection Rate
Novel Endocuff-assisted Colonoscopy Significantly Increases the Polyp Detection Rate a Randomized Controlled Trial. Erwin Biecker, MD, PhD, Martin Floer, MD, Achim Heinecke, PhD, Philipp Ströbel, MD, Rita Böhme, MD, Michael Schepke, MD, and Tobias Meister, MD. Journal of Clinical Gastroenterology 2014 Jun 11. [Epub ahead of print]
A prospective randomised two centre trial of 498 patients referred for colorectal cancer screening. The adenoma detection rate (ADR) using the ENDOCUFF™ was 36%compared to 28% with standard colonoscopy P=0.043 this is a difference of 8%, an increase in adenoma detection of 29%. The number of adenomas detected per patient using the Endocuff increased by 86% [2.00 (IQR, 1.00-3.00) vs. 1.00 (IQR, 1.00-2.00), P=0.002]. ENDOCUFF™ assisted colonoscopy was particularly effective in the caecum and sigmoid colon. Total colonoscopy was achieved in 98% in each group. Ileal intubation was achieved in 175 cases using the ENDOCUFF™ compared with 176 patients with standard colonoscopy NS (P=0.741) the overall procedure time took 1.5 minutes longer with the ENDOCUFF™ (23min vs. 21.5min, P=0.04) this relatively small increase in time was attributed to the greater number of polyps that were resected. There were no major complications in either group.
Conclusion:The ENDOCUFF™ is safe, reliable, and easy to handle and has the potential to improve the efficiency of colonoscopy in adenoma detection thus reducing the incidence of colorectal cancer.