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Higher Adenoma Detection Rates with Endocuff-Assisted Colonoscopy

Higher Adenoma Detection Rates with Endocuff-Assisted Colonoscopy A Randomized Controlled Multicenter Trial

Martin Floer, Erwin Biecker, Rudiger Fitzlaff, Hermann Röming, Detlev Ameis, Achim Heinecke, Steffen Kunsch, Volker Ellenrieder, Philipp Ströbel, Michael Schepke, Tobias Meister PLoS ONE 9(12): e114267. doi:10.1371/journal.pone. 0114267

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255000/

This four centre prospective trial randomised 500 subjects to standard colonoscopy or ENDOCUFF™ assisted colonoscopy the primary outcome measure was the adenoma detection rate (ADR). The ADR increased from 21% to 35% with the use of the ENDOCUFF™ (p = 0.0001) an absolute increase of 14% and a relative improvement of 74%. The total number of adenomas detected rose from 88 to 144, a relative improvement of 64%.The procedure and withdrawal times did not differ. Caecal and ileum intubation rates were similar. No major adverse events occurred in either group.

Conclusion: the ENDOCUFF™ is safe, and substantially improves adenoma detection and removal without lengthening operator time or reducing caecal or ileal intubation.

" The Endocuff is feasible, safe, reliable and easy to handle and might have potential to reduce the incidence of colorectal cancer "

Dr Meister, Clinical Endocrirology News Digital Network

" ...potential to become an indispensable tool of every colon cancer surveillance program "

Dr Meister, UEGW 2014

" My colleagues and I have definitely found polyps that they didn’t see with the forward view. We feel we were doing an excellent exam with current colonoscopy and that this made it better. "

Outpatient Surgery Magazine

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